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Easify Your Lyo Process

Process Control with Product Temperature Monitoring with Tempris’ Unique Wireless Sensor Technology.

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Tempris – Product Temperature Control in Lyophilization

Easify Your Lyo Process with Proven Temperature Control – Faster Launches, Lower COGs

Tempris is the innovation leader in wireless in-process product temperature control for freeze-drying – with over 15 years of experience in pharmaceutical practice. Tempris connects lab, tech transfer, and GMP production through an identical temperature profile – regardless of location, batch size, or equipment.

Pharma and biotech companies use Tempris as a scalable, PAT-enabled platform to:

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Significantly reduce time-to-market

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Strategically lower manufacturing costs (COGs)

[/fusion_li_item][fusion_li_item icon=”” awb-switch-editor-focus=”” iconcolor=”” hue=”” saturation=”” lightness=”” alpha=”” circlecolor=””]

Standardize, validate, and integrate global processes without technology disruption

[/fusion_li_item][/fusion_checklist][fusion_text columns=”” column_min_width=”” column_spacing=”” rule_style=”” rule_size=”” rule_color=”” hue=”” saturation=”” lightness=”” alpha=”” user_select=”” awb-switch-editor-focus=”” content_alignment_medium=”” content_alignment_small=”” content_alignment=”” hide_on_mobile=”small-visibility,medium-visibility,large-visibility” sticky_display=”normal,sticky” class=”” id=”” width_medium=”” width_small=”” width=”” min_width_medium=”” min_width_small=”” min_width=”” max_width_medium=”” max_width_small=”” max_width=”” margin_top=”20″ margin_right=”” margin_bottom=”” margin_left=”” fusion_font_family_text_font=”” fusion_font_variant_text_font=”” font_size=”” line_height=”” letter_spacing=”” text_transform=”” text_color=”” animation_type=”” animation_direction=”left” animation_color=”” animation_speed=”0.3″ animation_delay=”0″ animation_offset=”” logics=””]With real-time data directly from the product, Tempris empowers strategic initiatives such as design for manufacturability, digital twins, and automated release decisions.

The result: Less risk. Faster product launches. Higher margins.

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NEW: LyoCLC® – Boost Freeze-Drying Efficiency by 25%

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Precise. Reproducible. Validated.

LyoCLC® revolutionizes freeze-drying with objective endpoint determination for primary drying. No guesswork, no excessive safety margins—just data-driven decisions for maximum efficiency.

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Faster drying times

[/fusion_li_item][fusion_li_item icon=”” awb-switch-editor-focus=”” iconcolor=”” hue=”” saturation=”” lightness=”” alpha=”” circlecolor=””]Cost savings through optimized processes[/fusion_li_item][fusion_li_item icon=”” awb-switch-editor-focus=”” iconcolor=”” hue=”” saturation=”” lightness=”” alpha=”” circlecolor=””]

Accelerated time-to-market & enhanced product quality

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Unlock the full potential of your freeze-dryer—with AI-powered precision.

Discover how LyoCLC® transforms your processes!

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Are you ready to revolutionize your freeze-drying process and take your product development to the next level?

Tempris sensor technology can help you streamline your processes and comply with FDA regulations, allowing you to get your product to market faster.

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See how Tempris Sensor Technology Works

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Fields of Application of the Tempris System

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Real-time Product Temperature Monitoring

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Hot and Cold Spot Monitoring

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Lyo-Cycle
Optimization

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Lyo-Cycle Scale-Up and Transfer

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Tempris Data for Regulatory Submission

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Measurement during Granulation

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margin_left_small=”” margin_top=”” margin_right=”30″ margin_bottom=”” margin_left=”30″ bordersize=”” bordercolor=”” borderradius=”” z_index=”” caption_style=”off” caption_align_medium=”none” caption_align_small=”none” caption_align=”none” caption_title=”” caption_text=”” caption_title_tag=”2″ fusion_font_family_caption_title_font=”” fusion_font_variant_caption_title_font=”” caption_title_size=”” caption_title_line_height=”” caption_title_letter_spacing=”” caption_title_transform=”” caption_title_color=”” caption_background_color=”” fusion_font_family_caption_text_font=”” fusion_font_variant_caption_text_font=”” caption_text_size=”” caption_text_line_height=”” caption_text_letter_spacing=”” caption_text_transform=”” caption_text_color=”” caption_border_color=”” caption_overlay_color=”” caption_margin_top=”” caption_margin_right=”” caption_margin_bottom=”” caption_margin_left=”” animation_type=”” animation_direction=”left” animation_color=”” animation_speed=”0.3″ animation_delay=”0″ 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Biopharmaceutical
Application

[/fusion_text][fusion_imageframe image_id=”6663″ aspect_ratio=”” custom_aspect_ratio=”100″ aspect_ratio_position=”” skip_lazy_load=”” lightbox=”no” gallery_id=”” lightbox_image=”” lightbox_image_id=”” alt=”icon for biopharmaceuticals” link=”” linktarget=”_self” hide_on_mobile=”small-visibility,medium-visibility,large-visibility” sticky_display=”normal,sticky” class=”” id=”” max_width=”70%” sticky_max_width=”” align_medium=”none” align_small=”none” align=”center” mask=”” custom_mask=”” mask_size=”” mask_custom_size=”” mask_position=”” mask_custom_position=”” mask_repeat=”” style_type=”” blur=”” stylecolor=”” hue=”” saturation=”” lightness=”” alpha=”” hover_type=”none” magnify_full_img=”” magnify_duration=”120″ scroll_height=”100″ scroll_speed=”1″ margin_top_medium=”” margin_right_medium=”” margin_bottom_medium=”” margin_left_medium=”” margin_top_small=”” margin_right_small=”” margin_bottom_small=”” margin_left_small=”” margin_top=”” margin_right=”30″ margin_bottom=”” margin_left=”30″ bordersize=”” bordercolor=”” borderradius=”” z_index=”” caption_style=”off” caption_align_medium=”none” caption_align_small=”none” caption_align=”none” caption_title=”” caption_text=”” caption_title_tag=”2″ fusion_font_family_caption_title_font=”” fusion_font_variant_caption_title_font=”” caption_title_size=”” caption_title_line_height=”” caption_title_letter_spacing=”” caption_title_transform=”” caption_title_color=”” caption_background_color=”” fusion_font_family_caption_text_font=”” fusion_font_variant_caption_text_font=”” caption_text_size=”” caption_text_line_height=”” caption_text_letter_spacing=”” caption_text_transform=”” caption_text_color=”” caption_border_color=”” caption_overlay_color=”” caption_margin_top=”” caption_margin_right=”” caption_margin_bottom=”” caption_margin_left=”” animation_type=”” animation_direction=”left” animation_color=”” animation_speed=”0.3″ animation_delay=”0″ animation_offset=”” filter_hue=”0″ filter_saturation=”100″ filter_brightness=”100″ 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us[/fusion_button][/fusion_builder_column][fusion_builder_column type=”1_4″ layout=”1_3″ align_self=”stretch” content_layout=”column” align_content=”space-between” valign_content=”flex-start” content_wrap=”wrap” spacing=”” center_content=”no” column_tag=”div” link=”” target=”_self” link_description=”” min_height=”” hide_on_mobile=”small-visibility,medium-visibility,large-visibility” sticky_display=”normal,sticky” class=”” id=”” background_image_id_medium=”” background_image_id_small=”” background_image_id=”” type_medium=”” type_small=”” flex_grow_medium=”” flex_grow_small=”” flex_grow=”” flex_shrink_medium=”” flex_shrink_small=”” flex_shrink=”” order_medium=”0″ order_small=”0″ spacing_left_medium=”” spacing_right_medium=”” spacing_left_small=”” spacing_right_small=”” spacing_left=”” spacing_right=”” margin_top_medium=”” margin_bottom_medium=”” margin_top_small=”” margin_bottom_small=”” margin_top=”” margin_bottom=”” padding_top_medium=”” padding_right_medium=”” padding_bottom_medium=”” 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background_color_small_hover=”” background_color_hover=”” background_color=”var(–awb-color1)” background_image_medium=”” background_image_small=”” background_image=”” lazy_load=”avada” skip_lazy_load=”” background_position_medium=”” background_position_small=”” background_position=”left top” background_repeat_medium=”” background_repeat_small=”” background_repeat=”no-repeat” background_size_medium=”” background_size_small=”” background_size=”” background_custom_size=”” background_custom_size_medium=”” background_custom_size_small=”” background_blend_mode_medium=”” background_blend_mode_small=”” background_blend_mode=”none” render_logics=”” sticky=”off” sticky_devices=”small-visibility,medium-visibility,large-visibility” sticky_offset=”” absolute=”off” absolute_top=”” absolute_right=”” absolute_bottom=”” absolute_left=”” filter_type=”regular” filter_hover_element=”self” filter_hue=”0″ filter_saturation=”100″ filter_brightness=”100″ filter_contrast=”100″ filter_invert=”0″ 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rule_size=”” rule_color=”” hue=”” saturation=”” lightness=”” alpha=”” content_alignment_medium=”” content_alignment_small=”” content_alignment=”” hide_on_mobile=”small-visibility,medium-visibility,large-visibility” sticky_display=”normal,sticky” class=”” id=”” margin_top=”30″ margin_right=”30″ margin_bottom=”10″ margin_left=”30″ fusion_font_family_text_font=”” fusion_font_variant_text_font=”” font_size=”” line_height=”” letter_spacing=”” text_transform=”” text_color=”” animation_type=”” animation_direction=”left” animation_color=”” animation_speed=”0.3″ animation_delay=”0″ animation_offset=”” logics=””]

Probiotics
Application

[/fusion_text][fusion_imageframe image_id=”6652″ aspect_ratio=”” custom_aspect_ratio=”100″ aspect_ratio_position=”” skip_lazy_load=”” lightbox=”no” gallery_id=”” lightbox_image=”” lightbox_image_id=”” alt=”icon for probiotics” link=”” linktarget=”_self” hide_on_mobile=”small-visibility,medium-visibility,large-visibility” sticky_display=”normal,sticky” class=”” id=”” max_width=”70%” sticky_max_width=”” align_medium=”none” align_small=”none” align=”center” mask=”” custom_mask=”” mask_size=”” mask_custom_size=”” mask_position=”” mask_custom_position=”” mask_repeat=”” style_type=”” blur=”” stylecolor=”” hue=”” saturation=”” lightness=”” alpha=”” hover_type=”none” magnify_full_img=”” magnify_duration=”120″ scroll_height=”100″ scroll_speed=”1″ margin_top_medium=”” margin_right_medium=”” margin_bottom_medium=”” margin_left_medium=”” margin_top_small=”” margin_right_small=”” margin_bottom_small=”” margin_left_small=”” margin_top=”” margin_right=”30″ margin_bottom=”” margin_left=”30″ bordersize=”” bordercolor=”” borderradius=”” z_index=”” caption_style=”off” caption_align_medium=”none” caption_align_small=”none” caption_align=”none” caption_title=”” caption_text=”” caption_title_tag=”2″ fusion_font_family_caption_title_font=”” fusion_font_variant_caption_title_font=”” caption_title_size=”” caption_title_line_height=”” caption_title_letter_spacing=”” caption_title_transform=”” caption_title_color=”” caption_background_color=”” fusion_font_family_caption_text_font=”” fusion_font_variant_caption_text_font=”” caption_text_size=”” caption_text_line_height=”” caption_text_letter_spacing=”” caption_text_transform=”” caption_text_color=”” caption_border_color=”” caption_overlay_color=”” caption_margin_top=”” caption_margin_right=”” caption_margin_bottom=”” caption_margin_left=”” animation_type=”” animation_direction=”left” animation_color=”” animation_speed=”0.3″ animation_delay=”0″ animation_offset=”” filter_hue=”0″ filter_saturation=”100″ filter_brightness=”100″ filter_contrast=”100″ filter_invert=”0″ filter_sepia=”0″ filter_opacity=”100″ filter_blur=”0″ filter_hue_hover=”0″ filter_saturation_hover=”100″ filter_brightness_hover=”100″ filter_contrast_hover=”100″ filter_invert_hover=”0″ filter_sepia_hover=”0″ filter_opacity_hover=”100″ filter_blur_hover=”0″]https://www.tempris.com/wp-content/uploads/2023/08/icon-probiotics.png[/fusion_imageframe][fusion_button link=”https://www.tempris.com/contact/” enable_hover_text_icon=”no” hover_text=”” title=”Contact us for further information” target=”_self” link_attributes=”” aria_role_button=”0″ alignment_medium=”” alignment_small=”” alignment=”left” modal=”” hide_on_mobile=”small-visibility,medium-visibility,large-visibility” sticky_display=”normal,sticky” class=”” id=”” color=”custom” button_gradient_top_color_hover=”” hue=”” saturation=”” lightness=”” alpha=”” button_gradient_top_color=”var(–awb-color1)” button_gradient_bottom_color_hover=”” button_gradient_bottom_color=”var(–awb-color1)” gradient_start_position=”” gradient_end_position=”” gradient_type=”” radial_direction=”” linear_angle=”180″ accent_hover_color=”” accent_color=”var(–awb-color6)” type=”” bevel_color=”” bevel_color_hover=”” border_top=”” border_right=”” border_bottom=”” border_left=”” border_radius_top_left=”” border_radius_top_right=”” border_radius_bottom_right=”” border_radius_bottom_left=”” border_hover_color=”” border_color=”” size=”” padding_top=”” padding_right=”” padding_bottom=”” padding_left=”” fusion_font_family_button_font=”” fusion_font_variant_button_font=”” font_size=”” line_height=”” letter_spacing=”” text_transform=”” stretch=”default” margin_top=”” margin_right=”” margin_bottom=”20″ margin_left=”” icon=”fa-arrow-right fas” hover_icon=”” icon_position=”right” icon_divider=”no” hover_transition=”none” animation_type=”” animation_direction=”left” animation_color=”” animation_speed=”0.3″ animation_delay=”0″ animation_offset=””]Contact us[/fusion_button][/fusion_builder_column][fusion_builder_column type=”1_4″ layout=”1_3″ align_self=”stretch” content_layout=”column” align_content=”space-between” valign_content=”flex-start” content_wrap=”wrap” spacing=”” center_content=”no” column_tag=”div” link=”” target=”_self” link_description=”” min_height=”” hide_on_mobile=”small-visibility,medium-visibility,large-visibility” sticky_display=”normal,sticky” class=”” id=”” background_image_id_medium=”” background_image_id_small=”” background_image_id=”” type_medium=”” type_small=”” flex_grow_medium=”” flex_grow_small=”” flex_grow=”” flex_shrink_medium=”” flex_shrink_small=”” flex_shrink=”” order_medium=”0″ order_small=”0″ spacing_left_medium=”” spacing_right_medium=”” spacing_left_small=”” spacing_right_small=”” spacing_left=”” spacing_right=”” margin_top_medium=”” margin_bottom_medium=”” margin_top_small=”” margin_bottom_small=”” margin_top=”” margin_bottom=”” padding_top_medium=”” padding_right_medium=”” padding_bottom_medium=”” 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background_color_small_hover=”” background_color_hover=”” background_color=”var(–awb-color1)” background_image_medium=”” background_image_small=”” background_image=”” lazy_load=”avada” skip_lazy_load=”” background_position_medium=”” background_position_small=”” background_position=”left top” background_repeat_medium=”” background_repeat_small=”” background_repeat=”no-repeat” background_size_medium=”” background_size_small=”” background_size=”” background_custom_size=”” background_custom_size_medium=”” background_custom_size_small=”” background_blend_mode_medium=”” background_blend_mode_small=”” background_blend_mode=”none” render_logics=”” sticky=”off” sticky_devices=”small-visibility,medium-visibility,large-visibility” sticky_offset=”” absolute=”off” absolute_top=”” absolute_right=”” absolute_bottom=”” absolute_left=”” filter_type=”regular” filter_hover_element=”self” filter_hue=”0″ filter_saturation=”100″ filter_brightness=”100″ filter_contrast=”100″ filter_invert=”0″ filter_sepia=”0″ filter_opacity=”100″ filter_blur=”0″ filter_hue_hover=”0″ filter_saturation_hover=”100″ filter_brightness_hover=”100″ filter_contrast_hover=”100″ filter_invert_hover=”0″ filter_sepia_hover=”0″ filter_opacity_hover=”100″ filter_blur_hover=”0″ transform_type=”regular” transform_hover_element=”self” transform_scale_x=”1″ transform_scale_y=”1″ transform_translate_x=”0″ transform_translate_y=”0″ transform_rotate=”0″ transform_skew_x=”0″ transform_skew_y=”0″ transform_origin=”” transform_scale_x_hover=”1″ transform_scale_y_hover=”1″ transform_translate_x_hover=”0″ transform_translate_y_hover=”0″ transform_rotate_hover=”0″ transform_skew_x_hover=”0″ transform_skew_y_hover=”0″ transition_duration=”300″ transition_easing=”ease” transition_custom_easing=”” 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rule_size=”” rule_color=”” hue=”” saturation=”” lightness=”” alpha=”” content_alignment_medium=”” content_alignment_small=”” content_alignment=”” hide_on_mobile=”small-visibility,medium-visibility,large-visibility” sticky_display=”normal,sticky” class=”” id=”” margin_top=”30″ margin_right=”30″ margin_bottom=”10″ margin_left=”30″ fusion_font_family_text_font=”” fusion_font_variant_text_font=”” font_size=”” line_height=”” letter_spacing=”” text_transform=”” text_color=”” animation_type=”” animation_direction=”left” animation_color=”” animation_speed=”0.3″ animation_delay=”0″ animation_offset=”” logics=””]

Peptides
Application

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RNA
Application

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Syros’ Experience with Tempris

„Tempris has been a wonderful partner to us, and their wireless technology was very helpful during our product development with an atypical process. They took time to understand our specific need and customized sensors and loading mechanisms for our specific application. Having a reliable and repeatable temperature measurement capability across multiple sites proved essential for transfer activities. Customer service was excellent along with support for both technical needs and parts.”

Syros Pharmaceuticals

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Sensor for Real-time Product Temperature Measurement

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Sensor placement in aseptic conditions

[/fusion_li_item][fusion_li_item icon=”” iconcolor=”” hue=”” saturation=”” lightness=”” alpha=”” circlecolor=””]

Smart sensor technology for all lyo scales

[/fusion_li_item][fusion_li_item icon=”” iconcolor=”” hue=”” saturation=”” lightness=”” alpha=”” circlecolor=””]Hot & cold spot monitoring[/fusion_li_item][fusion_li_item icon=”” iconcolor=”” hue=”” saturation=”” lightness=”” alpha=”” circlecolor=””]

No heat input to product

[/fusion_li_item][fusion_li_item icon=”” iconcolor=”” hue=”” saturation=”” lightness=”” alpha=”” circlecolor=””]

Retrofittable in nearly every freeze-dryer

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We specifically designed Tempris temperature sensors for the monitoring and optimization of freeze-drying processes. They have proven their reliability in many industrial and academic applications. Tempris sensors have a variety of advantages over other sensors measuring temperature in freeze drying

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Tempris Technology for Product Temperature Measurement

Tempris – Temperature remote interrogation system

The Tempris Lyophilization Monitoring Software TLM is used to control the interrogation unit (TIRU3), record data, set all parameters, visualize and export data. TLM gets the data of the Tempris Interrogation Unit TIRU3 which in turn gets temperature data from the antennas in the freeze-dryer. The antennas collect all the temperatures which are measured by the quartz based sensor (operating on the principle of temperature dependent resonance).

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Tempris fits all Primary Packaging

Tempris sensors are offered in different sizes to fit all types of primary packaging such as different-sized vials, DC syringes, etc.

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Dual chamber cartridges DCC (Magazine)

[/fusion_li_item][fusion_li_item icon=”” iconcolor=”” hue=”” saturation=”” lightness=”” alpha=”” circlecolor=””]

Lyo Trays (metal or plastic)

[/fusion_li_item][fusion_li_item]Lyoguard (Gore-tex) and others[/fusion_li_item][fusion_li_item icon=”fa-check fas” iconcolor=”” hue=”” saturation=”” lightness=”” alpha=”” circlecolor=”var(–awb-color6)”]

Double chamber (DC) syringes

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Pfizer’s Experience with Tempris

„Tempris wireless sensors allow placement of temperature sensors in any location within a freeze-dryer. They are also the sensor of choice if product temperatures of edge vials are monitored. Tempris sensors do not release heat while thermocouples or data loggers can transfer some heat into the product (very notable for edge vials), obscuring the actual product temperature. It is especially important if small fill volumes are used as readings of thermocouples and data loggers from the edge vials produce uncertain temperature profiles.”

Pfizer

[/fusion_text][fusion_button link=”” title=”” target=”_self” link_attributes=”” alignment_medium=”” alignment_small=”” alignment=”center” modal=”Pfizer-Testimonial” hide_on_mobile=”small-visibility,medium-visibility,large-visibility” sticky_display=”normal,sticky” class=”” id=”” color=”custom” button_gradient_top_color_hover=”” hue=”” saturation=”” lightness=”” alpha=”” button_gradient_top_color=”var(–awb-color1)” button_gradient_bottom_color_hover=”” button_gradient_bottom_color=”var(–awb-color1)” gradient_start_position=”” gradient_end_position=”” gradient_type=”” radial_direction=”” linear_angle=”180″ accent_hover_color=”” accent_color=”var(–awb-color6)” type=”” bevel_color=”” bevel_color_hover=”” border_top=”” border_right=”” border_bottom=”” border_left=”” border_radius_top_left=”” border_radius_top_right=”” border_radius_bottom_right=”” border_radius_bottom_left=”” border_hover_color=”” border_color=”” size=”” padding_top=”” padding_right=”” padding_bottom=”” padding_left=”” fusion_font_family_button_font=”” fusion_font_variant_button_font=”” font_size=”” line_height=”” letter_spacing=”” text_transform=”” stretch=”default” margin_top=”” margin_right=”” margin_bottom=”” margin_left=”” icon=”” icon_position=”left” icon_divider=”no” hover_transition=”none” animation_type=”” animation_direction=”left” animation_color=”” animation_speed=”0.3″ animation_delay=”0″ animation_offset=””]Read more[/fusion_button][fusion_modal name=”Pfizer-Testimonial” title=”Pfizer Testimonial” size=”large” background=”” hue=”” saturation=”” lightness=”” alpha=”” border_color=”” show_footer=”yes” class=”” id=””][fusion_testimonials design=”classic” navigation=”no” speed=”” backgroundcolor=”” textcolor=”” random=”” hide_on_mobile=”small-visibility,medium-visibility,large-visibility” class=”” id=””][fusion_testimonial name=”” avatar=”none” image=”” image_id=”” image_border_radius=”” company=”Pfizer Inc., Pharmaceutical R&D” link=”https://www.pfizer.com/” target=”_blank”]Vaccines becomes an important part of public health. They play an essential role in preventing the spread of infectious diseases and have saved millions of lives worldwide. Most of vaccines, however, are very sensitive to temperature and need to be lyophilized to remain effective. Pfizer is one of the largest vaccine manufacturers of the world.

In order to develop a robust manufacturing process significant efforts need to be made to ensure the quality of the product. We typically design lyophilization process in such way that even relatively wide variability of process parameters during manufacturing do not impact vaccine quality. We perform robust experiments at laboratory scale generating a wide product temperature design space (and wide range of process parameters associated with it) which produce product with acceptable quality. We also make sure that product quality attributes remain within specification for a desired shelf life for all samples generated during robustness study.

When we transfer lyophilization process we are making sure that product temperature at large scale remains within product design space generated during robustness study. This guarantees that stability profile of commercial material would be similar to that in laboratory study. Measurement of product temperature in laboratory dryer is easy and routine task. It is very difficult, however, to measure product temperature on the commercial scale dryer, especially, when it is equipped with automated vial loading system (ALUS).

Tempris, wireless sensor, allows placement of temperature sensors in any location within freeze-dryer. It is also a sensor of choice if product temperature of edge vials is monitored. Tempris sensor is not releasing heat while wired temperature sensors (thermocouples or data loggers) can transfer some heat into the product (very notable for the edge vials), obscuring the actual product temperature. It is especially very important if small fill volume is used when readings of thermocouples and data loggers from the edge vials produce uncertain temperature profiles.

Recently, we performed large scale experiments for one of our vaccine candidates using Tempris to ensure robustness of our process at scale. We demonstrated that product temperature profiles for both edge and center vials remain within design space, confirmed during laboratory robustness study. This provides insurance that commercial process will produce a product with the desired quality and provides strong support for our regulatory application.[/fusion_testimonial][/fusion_testimonials][/fusion_modal][/fusion_builder_column][/fusion_builder_row][/fusion_builder_container][fusion_builder_container type=”flex” hundred_percent=”no” hundred_percent_height=”no” min_height_medium=”” min_height_small=”” min_height=”” hundred_percent_height_scroll=”no” align_content=”stretch” flex_align_items=”flex-start” flex_justify_content=”flex-start” flex_column_spacing=”” hundred_percent_height_center_content=”yes” equal_height_columns=”no” container_tag=”div” menu_anchor=”” hide_on_mobile=”small-visibility,medium-visibility,large-visibility” status=”published” publish_date=”” class=”” id=”” margin_top_medium=”” margin_bottom_medium=”” margin_top_small=”” margin_bottom_small=”” margin_top=”0″ margin_bottom=”” padding_top_medium=”” padding_right_medium=”” padding_bottom_medium=”” 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Tempris Products – Product Temperature Measurement for all Lyo Scales

Lyo-cycle development in the laboratory establishes the base for the freeze drying cycle and subsequent optimization. When the product moves to a larger freeze-dryer, to a different type of freeze-dryer or simply to cGMP environment it was often necessary to change the Tp measurement technology. This causes problems or limitations with respect of the comparability of the obtained data. 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Laboratory Freeze-Dryer

Typical Shelf Size:
1 – 5 SQFT
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Pilot Freeze-Dryer

Typical Shelf Size:
10 – 50 SQFT
1 – 5 SQM[/fusion_text][fusion_imageframe image_id=”5640″ aspect_ratio=”” custom_aspect_ratio=”100″ aspect_ratio_position=”” skip_lazy_load=”” lightbox=”no” gallery_id=”” lightbox_image=”” lightbox_image_id=”” alt=”Product temperature measurement during lyophilization with Tempris sensors in Pilot Scale” link=”” linktarget=”_self” hide_on_mobile=”small-visibility,medium-visibility,large-visibility” sticky_display=”normal,sticky” class=”” id=”” max_width=”” sticky_max_width=”” align_medium=”none” align_small=”none” align=”none” mask=”” custom_mask=”” mask_size=”” mask_custom_size=”” mask_position=”” mask_custom_position=”” mask_repeat=”” style_type=”” blur=”” stylecolor=”” hue=”” saturation=”” lightness=”” alpha=”” hover_type=”none” magnify_full_img=”” magnify_duration=”120″ scroll_height=”100″ scroll_speed=”1″ margin_top_medium=”” margin_right_medium=”” margin_bottom_medium=”” margin_left_medium=”” margin_top_small=”” margin_right_small=”” margin_bottom_small=”” margin_left_small=”” 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and Transfer[/fusion_button][/fusion_builder_column][fusion_builder_column type=”1_3″ layout=”1_3″ align_self=”auto” content_layout=”column” align_content=”flex-start” valign_content=”flex-start” content_wrap=”wrap” spacing=”” center_content=”no” column_tag=”div” link=”” target=”_self” link_description=”” min_height=”” hide_on_mobile=”small-visibility,medium-visibility,large-visibility” sticky_display=”normal,sticky” class=”” id=”” background_image_id_medium=”” background_image_id_small=”” background_image_id=”” type_medium=”” type_small=”” order_medium=”0″ order_small=”0″ spacing_left_medium=”” spacing_right_medium=”” spacing_left_small=”” spacing_right_small=”” spacing_left=”” spacing_right=”” margin_top_medium=”” margin_bottom_medium=”” margin_top_small=”” margin_bottom_small=”” margin_top=”” margin_bottom=”” padding_top_medium=”” padding_right_medium=”” padding_bottom_medium=”” padding_left_medium=”” padding_top_small=”” padding_right_small=”” padding_bottom_small=”” 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Production Freeze-Dryer

Typical Shelf Size:
100 – 500 SQFT
10 – 50 SQM

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button_gradient_bottom_color_hover=”” button_gradient_bottom_color=”var(–awb-color1)” gradient_start_position=”” gradient_end_position=”” gradient_type=”” radial_direction=”” linear_angle=”180″ accent_hover_color=”” accent_color=”var(–awb-color6)” type=”” bevel_color=”” bevel_color_hover=”” border_top=”” border_right=”” border_bottom=”” border_left=”” border_radius_top_left=”” border_radius_top_right=”” border_radius_bottom_right=”” border_radius_bottom_left=”” border_hover_color=”” border_color=”” size=”” padding_top=”20″ padding_right=”” padding_bottom=”20″ padding_left=”” fusion_font_family_button_font=”” fusion_font_variant_button_font=”” font_size=”” line_height=”” letter_spacing=”” text_transform=”” stretch=”default” margin_top=”15″ margin_right=”” margin_bottom=”” margin_left=”” icon=”fa-arrow-right fas” icon_position=”right” icon_divider=”no” hover_transition=”none” animation_type=”” animation_direction=”left” animation_color=”” animation_speed=”0.3″ animation_delay=”0″ 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Automated Sensor Loading by Robot

Fully automated aseptic sensor loading by robot according to GMP Annex 1 ensures the highest aseptic safety level. Each sensor is checked for the correct vial-size, identified and recorded for accurate process repetition and batch comparison. Pre-prepared vials with sensors are loaded automatically in the predefined critical positions.

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saturation=”” lightness=”” alpha=”” animated_text_color=”” text_shadow=”no” text_shadow_vertical=”” text_shadow_horizontal=”” text_shadow_blur=”0″ text_shadow_color=”” text_stroke=”no” text_stroke_size=”1″ text_stroke_color=”” text_overflow=”none” margin_top_medium=”” margin_right_medium=”” margin_bottom_medium=”” margin_left_medium=”” margin_top_small=”” margin_right_small=”” margin_bottom_small=”” margin_left_small=”” margin_top=”” margin_right=”” margin_bottom=”” margin_left=”” margin_top_mobile=”” margin_bottom_mobile=”” gradient_font=”no” gradient_start_color=”” gradient_end_color=”” gradient_start_position=”0″ gradient_end_position=”100″ gradient_type=”linear” radial_direction=”center center” linear_angle=”180″ highlight_color=”” style_type=”default” sep_color=”” link_color=”” link_hover_color=”” animation_type=”” animation_direction=”left” animation_color=”” animation_speed=”0.3″ animation_delay=”0″ animation_offset=””]

Tempris Services

[/fusion_title][fusion_text columns=”” column_min_width=”” column_spacing=”” rule_style=”” rule_size=”” rule_color=”” hue=”” saturation=”” lightness=”” alpha=”” content_alignment_medium=”” content_alignment_small=”” content_alignment=”” hide_on_mobile=”small-visibility,medium-visibility,large-visibility” sticky_display=”normal,sticky” class=”” id=”” margin_top=”” margin_right=”” margin_bottom=”” margin_left=”” fusion_font_family_text_font=”” fusion_font_variant_text_font=”” font_size=”” line_height=”” letter_spacing=”” text_transform=”” text_color=”” animation_type=”” animation_direction=”left” animation_color=”” animation_speed=”0.3″ animation_delay=”0″ animation_offset=”” logics=””]Tempris offers a wide range of additional services to easify your process and ensure regulatory issues. We accompany you from the decision to measure temperature, through installation and maintenance, to optimising your freeze-drying process with accurate temperature data. Our service and support includes:[/fusion_text][/fusion_builder_column][fusion_builder_column type=”1_2″ layout=”1_2″ align_self=”auto” content_layout=”column” align_content=”flex-start” valign_content=”flex-start” content_wrap=”wrap” spacing=”” center_content=”no” column_tag=”div” link=”” target=”_self” link_description=”” min_height=”” hide_on_mobile=”small-visibility,medium-visibility,large-visibility” sticky_display=”normal,sticky” class=”” id=”” type_medium=”” type_small=”” order_medium=”0″ order_small=”0″ dimension_spacing_medium=”” dimension_spacing_small=”” dimension_spacing=”” dimension_margin_medium=”” dimension_margin_small=”” margin_top=”” margin_bottom=”” padding_medium=”” padding_small=”” padding_top=”” padding_right=”” padding_bottom=”” padding_left=”” hover_type=”none” border_sizes=”” border_color_hover=”” border_color=”” border_style=”solid” border_radius=”” box_shadow=”no” dimension_box_shadow=”” box_shadow_blur=”0″ box_shadow_spread=”0″ box_shadow_color=”” box_shadow_style=”” z_index_hover=”” z_index=”” overflow=”” background_type=”single” gradient_start_color=”” gradient_end_color=”” gradient_start_position=”0″ gradient_end_position=”100″ gradient_type=”linear” radial_direction=”center center” linear_angle=”180″ background_color_medium=”” background_color_small=”” background_color_hover=”” background_color=”” background_image_medium=”” background_image_small=”” background_image=”” background_image_id_medium=”” background_image_id_small=”” background_image_id=”” lazy_load=”avada” skip_lazy_load=”” background_position_medium=”” background_position_small=”” background_position=”left top” background_repeat_medium=”” background_repeat_small=”” background_repeat=”no-repeat” background_size_medium=”” background_size_small=”” background_size=”” background_custom_size=”” background_custom_size_medium=”” background_custom_size_small=”” background_blend_mode_medium=”” background_blend_mode_small=”” background_blend_mode=”none” render_logics=”” sticky=”off” sticky_devices=”small-visibility,medium-visibility,large-visibility” sticky_offset=”” absolute=”off” absolute_props=”” filter_type=”regular” filter_hover_element=”self” filter_hue=”0″ filter_saturation=”100″ filter_brightness=”100″ filter_contrast=”100″ filter_invert=”0″ filter_sepia=”0″ filter_opacity=”100″ filter_blur=”0″ filter_hue_hover=”0″ filter_saturation_hover=”100″ filter_brightness_hover=”100″ filter_contrast_hover=”100″ filter_invert_hover=”0″ filter_sepia_hover=”0″ filter_opacity_hover=”100″ filter_blur_hover=”0″ transform_type=”regular” transform_hover_element=”self” transform_scale_x=”1″ transform_scale_y=”1″ transform_translate_x=”0″ transform_translate_y=”0″ transform_rotate=”0″ transform_skew_x=”0″ transform_skew_y=”0″ transform_scale_x_hover=”1″ transform_scale_y_hover=”1″ transform_translate_x_hover=”0″ transform_translate_y_hover=”0″ transform_rotate_hover=”0″ transform_skew_x_hover=”0″ transform_skew_y_hover=”0″ transform_origin=”” transition_duration=”300″ transition_easing=”ease” transition_custom_easing=”” motion_effects=”” scroll_motion_devices=”small-visibility,medium-visibility,large-visibility” animation_type=”” animation_direction=”left” animation_color=”” animation_speed=”0.3″ animation_delay=”0″ animation_offset=”” last=”false” border_position=”all” first=”true” spacing_right=””][fusion_title title_type=”text” loop_animation=”once” rotation_effect=”bounceIn” display_time=”1200″ highlight_effect=”circle” highlight_width=”9″ highlight_top_margin=”0″ before_text=”” rotation_text=”” highlight_text=”” after_text=”” title_link=”off” link_url=”” link_target=”_self” hide_on_mobile=”small-visibility,medium-visibility,large-visibility” sticky_display=”normal,sticky” class=”” id=”” content_align_medium=”” content_align_small=”” content_align=”left” size=”3″ animated_font_size=”” fusion_font_family_title_font=”” fusion_font_variant_title_font=”” font_size=”” line_height=”” letter_spacing=”” text_transform=”” text_color=”” hue=”” saturation=”” lightness=”” alpha=”” animated_text_color=”” text_shadow=”no” text_shadow_vertical=”” text_shadow_horizontal=”” text_shadow_blur=”0″ text_shadow_color=”” text_stroke=”no” text_stroke_size=”1″ text_stroke_color=”” text_overflow=”none” margin_top_medium=”” margin_right_medium=”” margin_bottom_medium=”” margin_left_medium=”” margin_top_small=”” margin_right_small=”” margin_bottom_small=”” margin_left_small=”” margin_top=”” margin_right=”” margin_bottom=”” margin_left=”” margin_top_mobile=”” margin_bottom_mobile=”” gradient_font=”no” gradient_start_color=”” gradient_end_color=”” gradient_start_position=”0″ gradient_end_position=”100″ gradient_type=”linear” radial_direction=”center center” linear_angle=”180″ highlight_color=”” style_type=”default” sep_color=”” link_color=”” link_hover_color=”” animation_type=”” animation_direction=”left” animation_color=”” animation_speed=”0.3″ animation_delay=”0″ animation_offset=””]

At Your Site

[/fusion_title][fusion_checklist type=”icons” icon=”” iconcolor=”var(–awb-color1)” hue=”” saturation=”” lightness=”” alpha=”” circle=”” circlecolor=”var(–awb-color6)” textcolor=”” size=”” item_padding_top=”” item_padding_right=”” item_padding_bottom=”” item_padding_left=”” divider=”yes” divider_color=”#e8f0fb” odd_row_bgcolor=”” even_row_bgcolor=”” margin_top=”” margin_right=”” margin_bottom=”20″ margin_left=”” hide_on_mobile=”small-visibility,medium-visibility,large-visibility” class=”” id=”” parent_dynamic_content=””][fusion_li_item]IQ/OQ Execution[/fusion_li_item][fusion_li_item]User Training / Technical Support[/fusion_li_item][fusion_li_item]Maintenance / Annual Inspection[/fusion_li_item][fusion_li_item]Measuring Device Calibration[/fusion_li_item][/fusion_checklist][/fusion_builder_column][fusion_builder_column type=”1_2″ layout=”1_2″ align_self=”auto” content_layout=”column” align_content=”flex-start” valign_content=”flex-start” content_wrap=”wrap” spacing=”” 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margin_top_medium=”” margin_right_medium=”” margin_bottom_medium=”” margin_left_medium=”” margin_top_small=”” margin_right_small=”” margin_bottom_small=”” margin_left_small=”” margin_top=”” margin_right=”” margin_bottom=”” margin_left=”” margin_top_mobile=”” margin_bottom_mobile=”” gradient_font=”no” gradient_start_color=”” gradient_end_color=”” gradient_start_position=”0″ gradient_end_position=”100″ gradient_type=”linear” radial_direction=”center center” linear_angle=”180″ highlight_color=”” style_type=”default” sep_color=”” link_color=”” link_hover_color=”” animation_type=”” animation_direction=”left” animation_color=”” animation_speed=”0.3″ animation_delay=”0″ animation_offset=””]

At Tempris HQ

[/fusion_title][fusion_checklist type=”icons” icon=”” iconcolor=”var(–awb-color1)” hue=”” saturation=”” lightness=”” alpha=”” circle=”” circlecolor=”var(–awb-color6)” textcolor=”” size=”” item_padding_top=”” item_padding_right=”” item_padding_bottom=”” item_padding_left=”” divider=”yes” divider_color=”#e8f0fb” odd_row_bgcolor=”” even_row_bgcolor=”” margin_top=”” margin_right=”” margin_bottom=”20″ margin_left=”” hide_on_mobile=”small-visibility,medium-visibility,large-visibility” class=”” id=”” parent_dynamic_content=””][fusion_li_item]Calibration with Traceability[/fusion_li_item][fusion_li_item]Remote User Training[/fusion_li_item][fusion_li_item]Remote Technical Support[/fusion_li_item][/fusion_checklist][/fusion_builder_column][fusion_builder_column type=”1_1″ layout=”1_1″ align_self=”auto” content_layout=”column” align_content=”flex-start” valign_content=”flex-start” content_wrap=”wrap” spacing=”” center_content=”no” column_tag=”div” link=”” target=”_self” link_description=”” 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Conferences – Meet Us Personally

Tempris regularly attends conferences and trade shows all over the world. We would be glad to meet you there and tell you more about our solution for product temperature measurement in lyophilization.

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